Including the most remarkable buildings alongside the Deira side of the Creek are the Deira Twin Towers, Dubai Creek Tower, Sheraton Dubai Creek, National Bank, and Chamber of Commerce. On the other side of Al Maktoum Bridge along Dubai Creek is Dubai Creek Park, one of the largest parks in Dubai.
The creek is also home to the Dubai Creek Golf & Yacht Club, comprising an 18-hole tournament golf course, clubhouses, residential development and the Park Hyatt hotel.
The creek's initial inlet into mainland Dubai is along the Deira Corniche and Al Ras areas of eastern Dubai and along the Al Shindagha area of western Dubai. It then progresses south-eastward through the mainland, passing through Port Saeed and Dubai Creek Park. The creek's natural ending is at the Ras Al Khor Wildlife Sanctuary, 14 kilometres (8.7 mi) from its origin at the Persian Gulf. The traditional form of transport between the eastern and western sections of Dubai via the creek was through abras, which continue to operate in Dubai. In addition, the eastern and western sections are linked via four bridges (Al Maktoum Bridge, Al Garhoud Bridge, Business Bay Crossing, and Floating Bridge) and one tunnel (Al Shindagha Tunnel).